Top Healthcare ETFs

Last Updated: 8/20/2025

Our combined factor score ranks all ETFs using a combination of value, momentum, quality, and low volatility. The ETFS with the highest scores and the greatest consistency across the factors will receive the best rankings.

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Healthcare ETFs with the Highest Score Using Our Multi-Factor System

Ticker	ETF Name	Total Assets	Expense Ratio	Total Holdings	Active Share vs. S&P 500	Active Fee	Active Share vs. Russell 2000	Size Exposure	Value Exposure	Quality Exposure	Multi-Factor Exposure	Low Volatility Exposure
PBE	Invesco Dynamic Biotech &Genome ETF	$243,172,900	0.58%	31	99.21%	0.58%	98.85%	76	25	29	54	48
XPH	SPDR SPDR S & P Pharmaceuticals ETF	$187,600,000	0.35%	42	97.16%	0.36%	98.50%	75	42	6	54	43
BMED	BlackRock Future Health ETF	$3,555,980	0.85%	149	94.70%	0.90%	97.20%	59	26	39	53	59
HTEC	Robo Global- Hlthcare Tech & Innovt ETF	$36,940,660	0.68%	69	97.04%	0.70%	98.28%	65	17	17	53	27
SBIO	ALPS Medical Breakthroughs ETF	$76,772,730	0.50%	95	99.62%	0.50%	95.33%	97	1	1	52	5
GNOM	Global X Genomics & Biotechnology ETF	$42,283,180	0.50%	1	98.08%	0.51%	98.60%	85	4	1	52	12
ARKG	ARK Genomic Revolution Multi-Sector ETF	$1,052,816,000	0.75%	41	99.37%	0.75%	98.80%	91	2	1	52	1
XBI	SPDR S & P Biotech ETF	$7,032,803,000	0.35%	139	98.33%	0.36%	93.79%	84	9	3	52	20
WDNA	WisdomTree BioRevolution ETF	$2,110,829	0.45%	92	95.56%	0.47%	98.15%	72	16	2	51	9
FTXH	First Trust Nasdaq Pharmaceuticals ET	$14,623,100	0.60%	51	95.24%	0.63%	97.63%	54	65	62	50	90

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