Top Healthcare ETFs

Last Updated: 7/26/2025

Our combined factor score ranks all ETFs using a combination of value, momentum, quality, and low volatility. The ETFS with the highest scores and the greatest consistency across the factors will receive the best rankings.

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Healthcare ETFs with the Highest Score Using Our Multi-Factor System

Ticker	ETF Name	Total Assets	Expense Ratio	Total Holdings	Active Share vs. S&P 500	Active Fee	Active Share vs. Russell 2000	Size Exposure	Value Exposure	Quality Exposure	Multi-Factor Exposure	Low Volatility Exposure
IHI	iShares Dow Jones U.S. Medical Devices Index Fund ETF	$4,315,655,000	0.40%	56	99.78%	0.40%	98.32%	66	19	88	68	77
FXH	First Trust Health Care AlphaDEX ETF	$853,583,600	0.62%	82	100.00%	0.62%	100.00%	54	67	51	63	72
PBE	Invesco Dynamic Biotech &Genome ETF	$243,111,200	0.58%	31	100.00%	0.58%	98.82%	76	17	15	55	47
FTXH	First Trust Nasdaq Pharmaceuticals ET	$14,663,660	0.60%	51	99.80%	0.60%	97.70%	55	63	62	55	91
BMED	BlackRock Future Health ETF	$3,554,589	0.85%	149	100.00%	0.85%	97.20%	60	25	33	53	62
HTEC	Robo Global- Hlthcare Tech & Innovt ETF	$36,104,140	0.68%	69	100.00%	0.68%	98.37%	64	16	11	52	26
XBI	SPDR S & P Biotech ETF	$7,032,465,000	0.35%	139	99.89%	0.35%	93.75%	84	8	2	51	18
SBIO	ALPS Medical Breakthroughs ETF	$77,607,130	0.50%	95	99.53%	0.50%	95.55%	98	2	1	49	5
HELX	Franklin Genomic Advancements ETF	$9,002,955	0.50%	66	100.00%	0.50%	98.03%	60	10	17	49	38
GNOM	Global X Genomics & Biotechnology ETF	$38,548,800	0.50%	1	100.00%	0.50%	98.89%	85	4	1	49	13

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