Top Healthcare ETFs

Last Updated: 10/7/2026

Our combined factor score ranks all ETFs using a combination of value, momentum, quality, and low volatility. The ETFS with the highest scores and the greatest consistency across the factors will receive the best rankings.

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Healthcare ETFs with the Highest Score Using Our Multi-Factor System

Ticker	ETF Name	Total Assets	Expense Ratio	Total Holdings	Active Share vs. S&P 500	Active Fee	Active Share vs. Russell 2000	Size Exposure	Value Exposure	Quality Exposure	Multi-Factor Exposure	Low Volatility Exposure
FXH	First Trust Health Care AlphaDEX ETF	$1,145,412,000	0.61%	75	93.11%	0.66%	99.95%	50	48	56	97	66
PPH	VanEck Pharmaceutical ETF	$954,490,800	0.36%	27	95.68%	0.38%	99.78%	26	66	76	95	96
IYH	iShares Dow Jones U.S. Health Care Index Fund ETF	$3,955,873,000	0.38%	104	91.48%	0.42%	100.00%	40	38	70	92	92
XLV	Health Care Select Sector SPDR Fund	$41,750,700,000	0.08%	63	90.61%	0.09%	99.86%	32	41	70	92	95
PJP	Invesco Dynamic Pharmaceuticals ETF	$488,012,200	0.57%	33	94.91%	0.60%	98.88%	50	45	40	90	87
VHT	Vanguard Health Care ETF - DNQ ETF	$18,313,910,000	0.09%	430	90.90%	0.10%	93.06%	63	39	60	90	90
FTXH	First Trust Nasdaq Pharmaceuticals ET	$1,050,879,000	0.60%	51	94.83%	0.63%	96.07%	49	41	55	88	87
IHE	iShares Dow Jones U.S. Pharmaceutical Index Fund ETF	$1,464,308,000	0.38%	60	96.62%	0.39%	97.76%	64	37	65	87	92
IXJ	iShares S&P Global Healthcare Index Fund ETF	$3,501,459,000	0.40%	125	91.00%	0.44%	99.74%	33	41	71	83	95
FBT	First Trust Arca Biotech Index Fund ETF	$2,949,974,000	0.55%	32	98.93%	0.56%	99.09%	61	14	48	72	47

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