Top Healthcare ETFs

Last Updated: 1/24/2026

Our combined factor score ranks all ETFs using a combination of value, momentum, quality, and low volatility. The ETFS with the highest scores and the greatest consistency across the factors will receive the best rankings.

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Healthcare ETFs with the Highest Score Using Our Multi-Factor System

Ticker	ETF Name	Total Assets	Expense Ratio	Total Holdings	Active Share vs. S&P 500	Active Fee	Active Share vs. Russell 2000	Size Exposure	Value Exposure	Quality Exposure	Multi-Factor Exposure	Low Volatility Exposure
PPH	VanEck Pharmaceutical ETF	$1,188,435,000	0.36%	27	99.83%	0.36%	99.67%	23	54	86	97	97
FTXH	First Trust Nasdaq Pharmaceuticals ET	$21,718,910	0.60%	51	99.82%	0.60%	96.57%	50	53	54	96	91
PJP	Invesco Dynamic Pharmaceuticals ETF	$273,397,300	0.57%	24	99.96%	0.57%	99.06%	63	53	43	92	88
FXH	First Trust Health Care AlphaDEX ETF	$946,499,800	0.62%	82	100.00%	0.62%	100.00%	51	61	54	89	66
FHLC	Fidelity MSCI Health Care Index ETF	$3,026,466,000	0.08%	329	100.00%	0.08%	93.19%	61	35	71	88	90
IXJ	iShares S&P Global Healthcare Index Fund ETF	$3,803,664,000	0.42%	128	100.00%	0.42%	99.68%	30	40	77	87	96
XLV	SPDR Health Care Select Sector SPDR Fund	$38,961,990,000	0.10%	66	99.78%	0.10%	99.89%	32	42	89	86	96
IHE	iShares Dow Jones U.S. Pharmaceutical Index Fund ETF	$935,145,000	0.40%	38	100.00%	0.40%	97.71%	63	33	58	84	89
IYH	iShares Dow Jones U.S. Health Care Index Fund ETF	$3,556,338,000	0.40%	116	100.00%	0.40%	100.00%	42	37	89	81	93
PBE	Invesco Dynamic Biotech &Genome ETF	$243,337,300	0.58%	31	100.00%	0.58%	98.51%	67	25	47	80	51

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